TaylorSizer™ - UltraSmall Particle Size Distribution Analyzer
เครื่องวิเคราะห์ขนาดและการกระจายตัวของอนุภาคขนาดเล็กมาก
TaylorSizer™ from Nanoscale Metrix is a compact, fully automated nanoparticle size distribution analyzer designed for precise characterization of ultrasmall nanoparticles and biomolecules below 50 nm. Using patented Size Distribution Taylor Dispersion Analysis (SD-TDA) technology, TaylorSizer™ delivers high-resolution, reproducible particle and molecular size distribution measurements in native liquid environments. The system requires only very low sample volumes and eliminates the need for labeling or complex sample preparation.
Beyond particle sizing, TaylorSizer™ also enables viscosity and stability measurements, providing comprehensive biophysical characterization for research and quality control laboratories. Its hydrodynamic analysis approach allows accurate detection of aggregation, subtle population differences, and surface coating effects that are often difficult to resolve using conventional light scattering or imaging techniques.
Developed for applications in biotechnology, pharmaceuticals, healthcare, and food science, TaylorSizer™ is ideal for nanoparticle analysis, formulation development, and routine QC testing.
Applications
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Ultra High Resolution Size Distribution
- Resolves fine particle populations and multimodal distributions
- Exceptional sensitivity in the 1–50 nm range
- Ideal for ultrasmall nanoparticles, proteins, and biomolecular assemblies
Label Free, Native Measurements
- No fluorescent or chemical labeling required
- Analyze samples in their native liquid state
- Preserves true particle behavior and interactions
Minimal Sample Preparation
- No fluorescent or chemical labeling required
- Analyze samples in their native liquid state
- Preserves true particle behavior and interactions
Fast & Reproducible Analysis
- Rapid measurement cycles suitable for R&D and QC
- Excellent repeatability for routine testing and batch comparison
- Supports method development and validation
Orthogonal to Light Scattering Techniques
- Complements DLS, NTA, and microscopy
- Provides additional insight into size distribution and aggregation
- Ideal for confirmatory and comparative studies
Specification
| Parameter | Specification |
| Pressure range | 10–3500 mbar, 1 mbar resolution |
| Inlet Trays | Buffer: 50 positions; Sample: 50 positions |
| Outlet Waste Vial | 20 positions |
| Autosampler temperature control | 5–55 °C |
| Temperature of Capillary Oven Compartment | 15–55 °C |
| Real-time UV-VIS diode array detector | 190–610 nm (UV version); 190–1010 nm (VIS version) |
| Laser Induced Fluorescence | Multiple wavelengths available (480, 535, 640 nm) |
| Software tools | Viscosity measurement; Method development assistance using abacuses |
| Size (W × D × H) | 43 × 48 × 66 cm |
| Weight | 43 kg |
| Power | 120–240 VAC, 50/60 Hz |
Software
- Simple and intuitive software interface for instrument control and data analysis
- Automatic relative quantification of particle subpopulations and polydispersity index (PDI) provided at the end of each measurement
- Clear data presentation through tabulated results, SD-TDA size distribution plots, and real-time Taylorgram monitoring
- Advanced data processing using a patented algorithm to compute accurate size distributions directly from experimental Taylorgrams
- Integrated viscosity measurement tool for extended biophysical characterization
- Dedicated method development assistance tool, incorporating Taylor-based abacus guidance for optimized and reproducible measurements
